Re(CO) 3 ([ 18 F]FEDA), a novel 18 F PET renal tracer: Radiosynthesis and preclinical evaluation
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چکیده
منابع مشابه
18 F-click labeling and preclinical evaluation of a new 18 F-folate for PET imaging
BACKGROUND The folate receptor (FR) is a well-established target for tumor imaging and therapy. To date, only a few 18 F-folate conjugates via 18 F-prosthetic group labeling for positron emission tomography (PET) imaging have been developed. To some extent, they all lack the optimal balance between efficient radiochemistry and favorable in vivo characteristics. METHODS A new clickable olate p...
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Introduction: Since the Adenosine-A3-receptor was identified in the late 1990 ́s, there is little data available describing its distribution in vivo. Recently, we introduced [ 18 F]FE@SUPPY as the first PET-tracer for this receptor. In the present investigation we translated this fluoroethyl-ester into the fluoroethyl-thioester [ 18 F]FE@SUPPY:2 (5-ethyl 2,4diethyl-3-((2-[ 18 F]fluoroethyl) sulf...
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A 61-year-old non-smoking woman presented with lowgrade fever of 1 year duration, which had remained undiagnosed after several first-line investigations. Intermittent non-productive cough and arthromyalgias were the only relevant complaints on history taking. Clinical examination was otherwise unremarkable. Laboratory findings only revealed increased C-reactive protein at 5 mg/dL. Of note, rena...
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a Pôle de Recherche Cardiovasculaire, Institut de Recherche Expérimentale et Clinique, Université catholique de Louvain, Brussels, Belgium b Division of Cardiology, Cliniques Universitaires Saint-Luc, Brussels, Belgium c Department of Nuclear Medicine, Imaging Institute, Cleveland Clinic, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH d Nuclear Med...
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ژورنال
عنوان ژورنال: Nuclear Medicine and Biology
سال: 2018
ISSN: 0969-8051
DOI: 10.1016/j.nucmedbio.2017.12.001